Welcome to the official web-site of the Laboratory of Biological Control and Antimicrobial Resistance of Orel State University named after I.S. Turgenev!

Antibiotics are normally understood to mean naturally formed metabolites of bacteria and fungi which inhibit the growth of or kill other microorganisms. Today, synthetically or genetically engineered substances with an antimicrobial effect are also included in this category. The antibiotics used for treatment purposes target various sites of action in the microorganisms.

Soon after the introduction of the first antibiotics in medicine, registant pathogens were observed whose growth was no longer influenced by substances which had previously inhibited or destroyed them. Microorganisms have come up with diverse counter-strategies in order to develop non-sensitivity (resistance) to these substances.

Microorganisms which can be transmitted directly between animals and humans or indirectly via foods to humans, so-called zoonotic agents, are of particular relevance when it comes to consumer health protection. Infections in humans triggered by these pathogens constitute a hazard for human health. An infection with these resistant bacteria leads to additional problems which may manifest in a prolonged course, increased severity of the disease and higher costs.

The main areas of the Laboratory of Biological Control and Antimicrobial Resistance (LBCAR) are:

• Antibiotic resistance study and testing;
• Collaboration in the analysis of infection chains;
• Molecular characterisation of antibiotic resistance determinats;
• Conduct of interlaboratory studies.